PREVALENCE OF THYROID DYSFUNCTION IN WOMEN WITH ABNORMAL UTERINE BLEEDING (AUB)
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Keywords
Abnormal uterine bleeding, Thyroid dysfunction, Hypothyroidism, Menorrhagia, Subclinical hypothyroidism, TSH, Reproductive health
Abstract
To determine the prevalence of thyroid dysfunction among women presenting with AUB and assess its association with different bleeding patterns.
Methods: This cross-sectional study was carried out at Bacha Khan Medical College with affiliated hospital, and Shaikh Zayed Women Hospital Lark Gynae Department Shaheed Muhtarma Benazir Bhutto Medical University, Chandka Medical College, Larkana Pakistan from January 2023 to January 2024. A total of 61 women aged 18–45 years with AUB were enrolled. Detailed clinical histories were taken, and thyroid function tests (TSH, FT3, FT4) were performed. Data were analyzed using SPSS version 25. The Chi-square test was used to determine associations, with p < 0.05 considered significant.
Results: Out of 61 women with AUB, 36.1% had thyroid dysfunction. Subclinical hypothyroidism was observed in 16.4%, overt hypothyroidism in 13.1%, and hyperthyroidism in 6.6%. Menorrhagia was the most frequent bleeding pattern and showed a significant association with thyroid abnormalities (p = 0.032). Although thyroid dysfunction was more prevalent among women over 30 years, no statistically significant correlation with age was found.
Conclusion: A substantial number of women with AUB had underlying thyroid disorders, particularly hypothyroidism. Routine thyroid function screening should be considered in the evaluation of AUB to ensure timely diagnosis and treatment.
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Dr Shabana Bano Soomro
Assistant Professor, OBGYN Unit 3, Shaheed Muhtarma Benazir Bhutto Medical University, Chandka Medical College, Shaikh Zayed Women Hospital, Larkana, Pakistan
Dr Sitara Sadia
Post Graduate Resident, Department of Obstetrics and Gynaecology, Mardan Medical Complex, Mardan, Pakistan
Dr Chaman Ara
Assistant Professor, Department of Obstetrics and Gynaecology, Women Medical and Dental College, Abbottabad, Pakistan
Dr Lyla Shaheen Naz
Senior Medical Officer, Department of Obstretics and Gynaecology, PAEC Hospital, Chashma Mianwali, Pakistan
Dr Shubana Tabasum
Medical Officer, Department of Obstetrics and Gynaecology, MCH PIMS, Islamabad, Pakistan