STUDY OF RELATIONSHIP BETWEEN PRESENCE OF LEFT ATRIAL THROMBUS IN PATIENTS WITH MITRAL STENOSIS WITH PLATELET LYMPHOCYTE RATIO TO IDENTIFY AT RISK PATIENT
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Abstract
: LA thrombus in Rheumatic Heart Disease -Mitral Stenosis cannot be explained only with the slowdown of blood flow and stasis in the left atrium associated with rheumatic mitral valve stenosis (RMVS) ; seen in around 20% of these with only valvular obstruction. In addition to LA stasis, inflammation, oxidative stress, platelet size, and an increase in activation have been found to be associated with thrombus formation . Recently, the platelet-to-lymphocyte ratio (PLR), known to be an inflammatory marker, has been found to be associated with various cardiovascular diseases.
References
2. Davison G, Greenland P. Predictors of left atrial thrombus in mitral valve disease. J Gen Intern Med 1991;6:108-12.
3. Saidi SJ, Motamedi MH. Incidence and factors influencing left atrial clot in patients with mitral stenosis and normal sinus rhythm. Heart 2004;90:1342-3.
4. Srimannarayana J, Varma RS, Satheesh S, Anilkumar R, Balachander J. Prevalence of left atrial thrombus in rheumatic mitral stenosis with atrial fibrillation and its response to anticoagulation: A transesophageal echocardiographic study. Indian Heart J2003;55:358-61.
5. Manning WJ, Weintraub RM, Waksmonski CA, Haering JM, Rooney PS,Maslow AD, et al. Accuracy of transesophageal echocardiography foridentifying left atrial thrombi. A prospective, intraoperative study. Ann Intern Med 1995;123:817-22.
6. Krishnamoorthy KM, Tharakan JA, Titus T, Ajithkumar VK, Bhat A, Harikrishnan SP, et al. Usefulness of transthoracic echocardiography for identification of left atrial thrombus before balloon mitral valvuloplasty. Am J Cardiol 2003;92:1132-4.
7. Abdelmoneim SS, Pellikka PA, Mulvagh SL. Contrast echocardiography for assessment of left ventricular thrombi. J Ultrasound Med 2014;33:1337-44.
8. Manjunath CN, Srinivasa KH, Ravindranath KS, Manohar JS, Prabhavathi B, Dattatreya PV, et al. Balloon mitral valvotomy in patients with mitral stenosis and left atrial thrombus. Catheter CardiovascInterv 2009;74:653-61.
9. Manjunath CN, Srinivasa KH, Panneerselvam A, Prabhavathi B, Ravindranath KS, Rangan K, et al. Incidence and predictors of left atrial thrombus in patients with rheumatic mitral stenosis and sinus rhythm: A transesophageal echocardiographic study. Echocardiography 2011;28: 457-60.
10. Balta S, Demirkol S, Kucuk U. The platelet lymphocyte ratio may be useful inflammatory indicator in clinical practice. Hemodial Int 2013; 17: 668-9.
11. Waehre T, Damas JK, Yndestad A, Tasken K, Pedersen TM, Smith C, et al. Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells -potential role of prostaglandin E2. Thromb Haemost 2004; 92: 1358-67.
12. Damas JK, Waehre T, Yndestad A, Otterdal K, Hognestad A, Solum NO, et al. Interleukin-7-mediated inflammation in unstable angina: possible role of chemokines and platelets. Circulation 2003; 107: 2670-6.
13. Akboğa MK, Akyel A, Şahinarslan A, Yayla C, Alsancak Y, Gokalp G, et al. Neutrophil-to-lymphocyte ratio is increased in patients withrheumatic mitral valve stenosis? Anatol J Cardiol 2015; 15: 380-4.
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Dr Pranamie Majumdar
Assistant Professor Department of Physiology Gauhati Medical College and Hospital , Guwahati
Dr Rondeep KN Sivam
Consultant Interventional Cardiologist , Narayana Superspeciality Hospitals , Guwahati
Dr Tony Ete
Associate Professor , Department of Cardiology , TRIHMS, Naharlagun
Dr M Kapoor
Professor , Department of Cardiology, NEIGRIHMS , Shillong
Dr A Malviya
Additional Professor, Department of Cardiology, NEIGRIHMS , Shillong
Dr A Mishra
Professor and HOD , Department of Cardiology, NEIGRIHMS , Shillong
Dr. Karto Ete
Assistant Professor, Department of General Medicine, TRIHMS, Naharlagun.