RESOLUTION OF HEPATORENAL SYNDROME IN A 50-YEAR-OLD MALE WITH TERLIPRESSIN THERAPY: A CASE REPORT

Main Article Content

Dr Nalla Varun Reddy
Dr Manish Mahlawat
Dr. Trishool Surya
Dr RP Gupta

Keywords

Hepatorenal syndrome, Terlipressin, Cirrhosis, Acute kidney injury, Terlipressin

Abstract

Background
Hepatorenal Syndrome (HRS) is a severe and potentially reversible renal dysfunction seen in patients  with advanced liver disease. Prompt diagnosis and treatment are essential to prevent progression and improve survival.


Case Presentation


We present the case of a 50-year-old male with decompensated cirrhosis who developed Type 1 HRS. The patient was treated with intravenous albumin and terlipressin. Significant clinical and biochemical improvement was noted within one week of therapy.


Conclusion
Early identification and initiation of terlipressin therapy can lead to complete resolution of
HRS, potentially reducing the need for dialysis and bridging patients to liver transplantation.

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References

1. Angeli P, et al. Diagnosis and management of acute kidney injury in patients with cirrhosis: Revised consensus recommendations. J Hepatol. 2015.
2. Boyer TD, et al. Terlipressin plus albumin improves renal function in hepatorenal syndrome. Gastroenterology2008.
3. European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Management of decompensated cirrhosis. J Hepatol. 2018.