ASSOCIATION OF PEDIATRIC PATIENTS’ SYMPTOMATOLOGY TO SARS-COV-2 SEROLOGY

Abstract

Background : To study the association of pediatric patients’ symptomatology to Sars-CoV-2 serology.

Subjects and Methods :This prospective cross sectional study was conducted at Karachi Adventist Hospital between January to August 2021. Patients count 232 enrolled from from OPD and IPD with fever, cough , difficulty in breathing , vomiting and diarrhea . Association of covid 19 serology with patients symptomatology and various study parameters was analyzed using Pearson chi square test . P-values less than 0.05 were considered statistically significant.

Results: Among enrolled subjects between five years till 15 year of age , 59.5 % were male with a male to female ratio of 1.46:1 . Among participants 80.6% had fever >100.4⁰F, 41.8% with cough, 31.5% with sore throat, 78.4% with respiratory rate <50 /min, 19.8% with sub costal recession, 44.4% with lose motions and 58.6% were found with complain of vomiting. Among samples with IgM+ serology, all  were with fever >100.4 F, 35% with Malaise , 75% with cough, 70% with sore throat, 60% with respiratory rate >50 /minute, 60% with sub costal recession, 40% with lose motion, 35% with vomiting.

Maternal education level , history of close contact with covid 19 proven cases showed statistically significant association with positive covid 19 serology .Cough , sore throat , respiratory rate and subcostal recession also showed statistically significant association with Sars-CoV-2 serology.

Conclusion : Our study showed positive serology in covid 19 suspects  who had predominantly respiratory complaints and had history of contact with PCR positive adults .