EVALUATE THE EFFECTIVENESS OF SCALING AND ROOT PLANNING WITH AND WITHOUT ADJUNCTIVE ANTIBIOTICS IN PESHAWAR
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Keywords
Abstract
Objective
To evaluate the clinical effectiveness of scaling and root planing (SRP) with and without adjunctive antibiotics systemic (amoxicillin + metronidazole) and local (minocycline microspheres) in the management of chronic periodontitis among patients in Peshawar
Methods
A randomized, single-blinded clinical trial was conducted with 90 systemically healthy participants diagnosed with chronic periodontitis. Subjects were divided equally into three groups: Group A (SRP alone), Group B (SRP + systemic antibiotics), and Group C (SRP + local antibiotics). Periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), and plaque index (PI) were recorded at baseline, 3 months, and 6 months. Data were analyzed using ANOVA and post-hoc Tukey tests.
Results
At 6 months, Groups B and C showed significantly greater improvements in PPD and CAL compared to Group A (p<0.01). Mean PPD reductions were 1.2 mm in Group A, 1.8 mm in Group B, and 1.7 mm in Group C. CAL gains followed a similar pattern. Both adjunctive antibiotic groups also showed greater reduction in BOP and PI. No major adverse events were observed, though mild gastrointestinal effects were reported in the systemic antibiotic group.
Conclusion
Adjunctive use of antibiotics, whether systemic or local, significantly enhances the clinical outcomes of SRP in chronic periodontitis patients. These findings support their selective use in moderate to severe cases, though antibiotic stewardship remains crucial, particularly in resource-limited settings like Peshawar.
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr Muhammad Jamil
BDS, DCD- Periodontology, CHPE, CHR, MHR Scholar, Demonstrator Khyber College of Dentistry, Peshawar
Dr Mahirah Iqbal
BDS, DCD- Periodontology, CHPE, C-Implant & Periodontal Esthetic Surgery, C-Orthodontics, Associate Professor of Periodontology, Head of Department, Peshawar Dental College, Peshawar
Syed Midhat Batool
MSc Periodontology, Assistant Professor, Bakhtawar Ameen Medical and Dental College,Multan
Dr Hussam Muhammad Ashfaq
BDS, MCPS Periodontology, CHPE, CHR, Chairperson and Associate Professor Periodontology, Khyber College of Dentistry, Peshawar, Pakistan
Rizwan Zafar Langrial
MSc Periodontology, Assistant Professor, Bakhtawar Amin Medical and Dental College, Multan, Pakistan
Dr Hafeezullah
BDS, RDS, BPS-17, Khyber Medical University- Institute of Dental Sciences, Pakistan