CORRELATION OF CANDIDAL SPECIES DIVERSITY BETWEEN NORMAL INDIVIDUALS AND HIV POSITIVE PATIENTS
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Abstract
Oral Candidiasis is considered one of the most prone opportunistic infection in patients of HIV (Human Immuno-deficiency Virus) infection in India. Candida being one of most important etiological agents for morbidity and mortality among patients with AIDS (Acquired Immuno-Deficiency Syndrome). Antifungal agents can effectively treat mucosal candidiasis, but however prolonged management can lead to colonization with minimal amount of species present along with other normal susceptible strains. (1)
Less commonly found candidal non-albicans species such as C. glabrata, C. parapsilosis, C. krusie and several other species may cause the disease. C.dubliniensis, a species almost similar to C. albicans might involve 15% of infections previously occurred due to C. albicans.
By the presence of variable candidal species as pathogenic organisms and a change in the development of susceptibility pattern of C. albicans, providing the need for isolation and identification of the particular causing organisms.
Oral colonizing species with drug resistant organisms is more common in advanced HIV infection warranting the discussion on different species of candida and their potential to harbor resistance against anti-fungal drugs. (2)
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Dr. Sourab Kumar
Professor, Department of Oral Pathology & Microbiology, D.Y.Patil School of Dentistry, Nerul, Navi Mumbai – 400706 Email id - sourab.kumar@dypatil.edu 9819614239
Dr. Abhishek Jadhav
Associate Professor, Department of Oral Pathology & Microbiology. D.Y.Patil School of Dentistry, Nerul, Navi Mumbai – 400706 Email id - abhishek.jadhav@dypatil.edu 9892007738
Dr. Treville Pereira
Vice-Dean,HOD,Professor, Department of Oral Pathology & Microbiology, D.Y.Patil School of Dentistry, Nerul, Navi Mumbai – 400706 Email id - treville.pereira@dypatil.edu 9821281458
Dr. Amarvaj Sindhu
D.Y.Patil School of Dentistry, Nerul, Navi Mumbai – 400706 Email id - santhoshi1994.amarvaj@gmail.com, 7981276903
Dr. Nikita Rai
D.Y.Patil School of Dentistry, Nerul, Navi Mumbai – 400706 Email id - rainiki7s@gmail.com
9324645272
Dr. Trisha Singh Sengar
D.Y.Patil School of Dentistry, Nerul, Navi Mumbai – 400706 Email id - trisha19sengar@gmail.com 8080450976