DOES VISCERAL FAT A RISK FACTOR ASSOCIATE WITH BONE DENSITY OF BACK PAIN PATIENTS IN LUMBAR DISC DEGENERATION?
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Keywords
Back Pain , Body Fat , Bone density , Disc degeneration, MRI
Abstract
Background: The impact of obesity and excess of visceral fat has been linked to bone metabolism. The objective of the study was relationship between visceral fat and bone density (BD) on back pain subjects with disc degeneration.
Methods: A total of 197 low back pain subjects between 30-70 years, undergone lumbosacral MRI (1.5T) were included. Based on MRI report, subjects were grouped into disc bulging (DBG) and Nerve compression Group (NCG) depending on degree of degeneration. Body fat were analysed by bioelectrical impedance analysis. Depending on the fat distribution, subjects were also subdivided into normal, overfat and obese.
Results: The result showed that in disc bulging patients there was a significant correlation between visceral fat with bone density and it was statistically significant (p=0.0002). In nerve compression group (NCG), visceral fat and bone density were statistically highly significant (p=0.000).
Conclusion: The degree of increment of visceral fat has a negative effect on bone density. So body composition analysis is of utmost importance in clinics for the preservation of bone health and severity of degeneration.
References
2. Hicks G.E, Morone N, and Weiner, D.K.(2009). Degenerative lumbar disc and facet disease in older adults: prevalence and clinical correlates. Spine (Phila Pa 1976). 34(12):1301–6.
3. Luoma K., Riihimaki H., Luukkonen R, Raininko R, Viikari-Juntura E, and Lamminen A.(2000). Low back pain in relation to lumbar disc degeneration. Spine.25(4):487–92.
4. Thompson J.P., Pearce R.H., Schechter M.T., Adams M.E., Tsang I.K., and Bishop P.B.(1990). Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine (Phila Pa 1976). 15(5):411–5.
5. Urquhart D.M., et al, (2014). Obesity is Associated with Reduced Disc Height in the Lumbar Spine but not at the Lumbosacral Junction. Spine. 39(16):E962-6 .
6. Pfirrmann C.W, Metzdorf A, Zanetti M, Hodler J, Boos N. (2001). Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976). 26(17):1873–8.
7. Kettler A., and Wilke H.J. (2006) Review of existing grading systems for cervical or lumbar disc and facet joint degeneration. Eur Spine J. 15(6):705–18.
8. M.C. Castañ Betancourt, et al.,(2013). Association of lumbar disc degeneration with osteoporotic fractures; the Rotterdam study and meta-analysis from systematic review, Bone . 57(1):284-289.
9. Mori Y., Hoshino K., Yokota K, et al.,(2006). Differences in the pathology of the metabolic syndrome with or without visceral fat accumulation: a study in pre-diabetic Japanese middle-aged men. Endocrine. 29(1):149–53.
10. Eastell R..O., Neill T.W., Hofbauer L.C., Langdahl B., Reid I..R., Gold D.T. and Cummings S.R.(2016).Postmenopausal osteoporosis. Nat Rev Dis Primers. 29(2):160-69.
11. Estell E.G. and Rosen C.J. (2021). Emerging insights into the comparative effectiveness of anabolic therapies for osteoporosis. Nat Rev Endocrinol. 17(1):31-46.
12. Calder P.C., Ahluwalia N., Brouns F., Buetler T., Clement K., Cunningham K, et al.,(2011) Dietary factors and low-grade inflammation in relation to overweight and obesity. Br J Nutr. 106(l3):5-78.
13. Zillikens M.C., et al.,(2010). The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density. Calcif Tissue Int. 86(2):116-25
14. Vizzuso S., et al.,(2021). Visceral Adiposity Index (VAI) in children and adolescents with obesity: no association with Daily Energy Intake but Promising Tool to identify metabolic syndrome (MetS). Nutrients. 13(2):413.
15. Zi-hao Chen,et al.,(2023). Bone mineral density saturation as influenced by the visceral adiposity index in adults older than 20 years: a population-based study Lipids Health Dis. 22(1):170.
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C K Sreeja
Department of Physiology, Jubilee Mission Medical College & Research Institute, Thrissur
V N Meena Devi
Department of Physics, Noorul Islam centre of Higher Education, Kumaracoil, Kanyakumari, District.
M K Aneesh
Department of Radiology, Jubilee Mission Medical College & Research Institute, Thrissur, Kerala.
Sreekanth K S
Department of Biochemistry, Sree Gokulam Medical College & Research Foundation, Trivandrum, Kerala.