EFFECT OF COVID-19 ON LOW PLATELET COUNT
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Keywords
Coronavirus Infections; Blood Platelets; Mean platelet volume; Mortality
Abstract
BACKGROUND: Easily accessible, inexpensive, and widely used laboratory tests that demonstrate the severity of COVID-19 are important. Therefore, in this study, we aimed to investigate the relationship between mortality in COVID-19 and platelets indices i.e. platelet count, Mean Platelet Volume (MPV), and platelet distribution width.
METHODS: In total, 100 COVID-19 patients were included in this study. The patients were divided into two groups. Patients with room air oxygen saturation < 90% were considered as severe COVID-19, and patients with ≥90% were considered moderate COVID-19. Patient medical records and the electronic patient data monitoring system were examined retrospectively. Analyses were performed using the SPSS statistical software. A p-value <0.05 was considered significant.
RESULTS: The patients’ mean age was 64.32 ± 16.07 years. According to oxygen saturation, 38 patients had moderate and 62 had severe COVID-19. Our findings revealed that oxygen saturation at admission and the MPV difference between the first and third days of hospitalization were significant parameters in COVID-19 patients for predicting mortality. While mortality was 8.4 times higher in patients who had oxygen saturation under 90 % at hospital admission, 1 unit increase in MPV increased mortality 1.76 times.
CONCLUSION: In addition to the lung capacity of patients, the mean platelet volume may be used as an auxiliary test in predicting the mortality in COVID-19 patients.
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Dr. Mohd Naushad Ansari
Assistant Professor, Venkateshwara Institute of Medical Sciences & Hospital, Rajabpur, Gajraula, Amroha
Dr. Deepa Sharma
Assistant Professor, Venkateshwara Institute of Medical Sciences & Hospital, Rajabpur, Gajraula, Amroha
Dr. Nilisha Sharma
Assistant Professor, Venkateshwara Institute of Medical Sciences & Hospital, Rajabpur, Gajraula, Amroha
Dr. Shachi
Professor, Venkateshwara Institute of Medical Sciences & Hospital, Rajabpur, Gajraula, Amroha