EVALUATION AND MONITORING OF BLOOD GLUCOSE AMONG PRE-DIABETIC ON STAPLE DIET SORGHUM (JAWAR) IN COAL CAPITAL OF INDIA, DHANBAD

Main Article Content

Dr. Mahto Hemanti Raghu
Dr. Neelam Agrawal
Dr. Ruchi Shree
Dr. S.K. Verma

Keywords

Pre-Diabetes, Sorghum (Jowar), Blood Glucose Monitoring, Fasting Blood Glucose, PPBG (Post-Prandial Blood Glucose), Dietary Intervention, Glycaemic Index, PPAR-γ Activation, Insulin Sensitivity, Millets and Diabetes, Functional Foods, Nutritional Therapy.

Abstract

Background: The number of people with type 2 diabetes mellitus (T2DM) is predicted to increase from 463 million in 2019 to 700 million by 2045, making it a serious global health concern. High-glycaemic diets based on refined cereals are associated with an increasing prevalence in India. Glycaemic control and insulin sensitivity may be enhanced by sorghum (jowar), a low-glycaemic, nutrient-dense millet high in bioactive compounds. In many areas, including Dhanbad, Jharkhand, its dietary use is still restricted in spite of this.


Aim:  The aim of this study was to assess and track how a staple diet high in sorghum (jowar) affects blood glucose levels in pre-diabetic people in Dhanbad, India's coal capital. In a region-specific setting, the study aims to ascertain whether regular sorghum consumption can support dietary interventions as a preventive strategy for pre-diabetes, delay the onset of diabetes, and contribute to glycaemic control.


Methodology: Two hundred pre-diabetic people in Dhanbad, aged 35 to 55, participated in this three-month study (August–October 2024). Jowar roti was served for dinner instead of rice or wheat for participants with FBG levels between 111 and 125 mg/dL and PPBG levels between 140 and 199 mg/dL. A fully autoanalyser was used to measure blood glucose once a month using the GOD-POD method.


Result: The mean PPBG dropped from 171.28 to 152.34 mg/dL and the mean FBG dropped from 117.88 to 111.84 mg/dL. Both parameters improved significantly (>10 mg/dL) in more than 85% of cases.


Conclusion: Pre-diabetics' glycaemic levels were improved by consuming jowar roti on a daily basis. A useful and culturally appropriate dietary strategy to help prevent Type 2 diabetes is sorghum.

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References

1. Pradeep M. Footprint of millets on type 2 diabetic mellitus: a short review. World Journal of Biology Pharmacy and Health Sciences 2023;14(01):280-4.
2. Park JH, Lee SH, Chung IM, et al. Sorghum extract exerts an anti-diabetic effect by improving insulin sensitivity via PPAR-γ in mice fed a high-fat diet. Nutr Res Pract 2012;6(4):322-7.
3. Anitha S, Kane-Potaka J, Tsusaka TW, et al. A systematic review and meta-analysis of the potential of millets for managing and reducing the risk of developing diabetes mellitus. Nutrients 2021;13(9):3277.
4. International Diabetes Federation. IDF Diabetes Atlas. 10th ed. Brussels, Belgium: IDF 2021.
5. American Diabetes Association. Standards of medical care in diabetes-2023. Diabetes Care 2023;46(Suppl 1):S1–291.
6. Yamauchi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001;7(8):941-6.
7. Hotamisligil GS. The role of TNFα and TNF receptors in obesity and insulin resistance. J Intern Med 1999;245(6):621-5.
8. Lehmann JM, Moore LB, Smith-Oliver TA, et al. An antidiabetic thiazolidinedione is a high affinity ligand for PPAR gamma. J Biol Chem 1995;270(22):12953-6.
9. Chung IM, Kim EH, Yeo MA, et al. Antidiabetic effects of three Korean sorghum phenolic extracts in normal and streptozotocin-induced diabetic rats. Food Res Int 2011;44(1):127-32.
10. Awika JM. Major cereal grains production and use around the world. In: Awika JM, Piironen V, Bean S, eds. Advances in cereal science: implications to food processing and health promotion. St. Paul: AACC International Press 2011:1-13.
11. Harvard TH. Chan School of Public Health. Carbohydrates and blood sugar. https://www.hsph.harvard.edu/nutritionsource/carbohydrates/carbohydrates-and-blood-sugar/
12. Poole N, Kane-Potaka J. The Smart Food triple bottom line – starting with diversifying staples. Agric Dev 2018;41:4-7.
13. Kim MJ, Hyun TK, Kim JS. The inhibitory effects of ethanol extracts from sorghum, foxtail millet and proso millet on α-glucosidase and α-amylase activities. Food Chem 2011;124(4):1647–51.
14. Ray TK, Mansell KM, Knight LC, et al. Long-term effects of dietary fiber on glucose tolerance and gastric emptying in noninsulin-dependent diabetic patients. Am J Clin Nutr 1983;37(3):376-81.
15. World Health Organization. WHO global report on effective interventions for noncommunicable disease prevention and control. Geneva: WHO 2021.
16. Anitha S, Tsusaka TW, Upadhyay S, et al. Millets can help tackle diabetes and metabolic disorders: a review of clinical and pre-clinical evidence. Nutrients 2021;13(11):3994.