PATTERN OF ANTIHYPERTENSIVE DRUGS PRESCRIBED IN A TERTIARY CARE HOSPITAL
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Keywords
Hypertension, Antihypertensive Drugs, Drug Prescription Audit.
Abstract
Background
A major cause of heart disease, stroke, and renal failure, hypertension is a major global health concern. Suboptimal adherence to treatment regimens and differences in prescribing patterns continue despite the availability of clinical guidelines and effective antihypertensive therapies. To encourage responsible drug use and enhance patient outcomes, tertiary care hospitals must assess prescription trends.
Aim: The purpose of this research was to examine how antihypertensive medication is prescribed in a tertiary care hospital and evaluate how well it follows accepted treatment protocols for managing hypertension.
Methodology: In a tertiary care hospital, a three-month retrospective observational study was carried out. To evaluate the pattern of antihypertensive medication use, 200 hypertensive patients' prescription records were examined. Patient demographics, prescribed medication classes, and therapy types (monotherapy or combination therapy) were among the data gathered.
Results: In this study of 200 patients, calcium channel blockers were the most often prescribed antihypertensive medications (35%), followed by beta-blockers (17.5%) and ACE inhibitors (25%). 35% of cases received combination therapy, whereas 65% of cases used monotherapy. Calcium channel blockers with ARBs and ACE inhibitors with diuretics were the most common drug combinations.
Conclusion: The study revealed the tertiary care hospital's prescribing practices mostly follow accepted treatment guidelines, with an emphasis on ACE inhibitors and calcium channel blockers. The results highlight the necessity of ongoing prescription practice monitoring to guarantee the prudent use of antihypertensive drugs and improve patient outcomes.
References
[2] Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003;289(19):2560-71.
[3] James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014;311(5):507-20.
[4] Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults. Hypertension 2018;71(6):e13-115.
[5] James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014;311(5):507-20.
[6] Whelton PK. The pharmacologic treatment of hypertension. N Engl J Med 2017;376(9):849-57.
[7] Burnier M, Egan BM. Adherence in hypertension. Circ Res 2019;124(7):1124-40.
[8] Patel R, Desai P, Patel K. Prescribing pattern of antihypertensive drugs in a tertiary care teaching hospital. International Journal of Basic & Clinical Pharmacology 2017;6(8):1934-9.
[9] Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nat Rev Nephrol 2020;16(4):223-37.
[10] Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. Lancet 2005;365(9455):217-23.
[11] Patel R, Desai P, Patel K. Prescribing pattern of antihypertensive drugs in a tertiary care teaching hospital. Int J Basic Clin Pharmacol 2017;6(8):1934-9.
[12] Saeed K, Rashid A. Pattern of antihypertensive drug utilization in tertiary care hospital. Pak J Pharm Sci 2019;32(1):123-9.
[13] James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014;311(5):507-20.
[14] Weber MA, Schiffrin EL, White WB, et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens 2014;16(1):14-26.
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr. Ramya K.N.
Assistant Professor, Department of Pharmacology, Sri Chamundeshwari Medical College Hospital and Research Institute, Channapatna, Karnataka, India.
Dr. Harshitha C.
Assistant Professor, Department of ENT, Sri Chamundeshwari Medical College Hospital and Research Institute, Channapatna, Karnataka, India.
Dr. Harshavardhana K.N.
Professor, Department of Dermatology, Kodagu Institute of Medical Sciences, Madikeri, Karnataka, India.