ANALYSIS OF EARLY AND LATE OUTCOMES OF TAPVC REPAIRS– A SINGLE SURGEON'S PERSPECTIVE OBSERVATIONAL STUDY

Main Article Content

Dr. Murtaza SM
Dr. Anurag Goyal
Amitabh satsangi
Dr. Devagourou Velayoudam

Keywords

TAPVC, surgical repair, outcome, mortality, observational study

Abstract

Introduction: Total anomalous pulmonary venous connection (TAPVC) is a congenital heart defect. Without surgical correction, it has a high mortality rate. Owing to the improved perioperative care and surgical techniques, the overall results have also improved. Our study assesses the early and late outcomes of TAPVC repairs done over last 10 years under a single surgeon.


Methods: Eighty-eight patients who were surgically treated for TAPVC over last 10 years from 01 June 2009 to 31 May 2019 by a single surgeon formed the basis of this retrospective observational study. The information regarding patient demographic details, pre-operative evaluation, surgical procedure, post-operative course and follow up after discharge was retrieved by searching operation theater registries, medical record sections and finally by patient follow up in outpatient department/telephonic follow up.


Results: Mean age and weight at surgery were 10.82 months and 5.27 kg respectively. Out of 88, 64 (72.7%) were male patients and 24 (27.3%) were females. 25% of the participants had Age ≤1 Month. The TAPVC anatomy was supra-cardiac in 41 (46.6%) cases, cardiac in 24 (27.3%), infra-cardiac in 14 (15.9%) and mixed in 9 (10.2%). Of the 88 TAPVC patients, 33 (37.5%) were obstructed at the time of operation. Twenty-nine (33%) patients had to be taken up for emergency TAPVC repair. The vertical vein was left open in 34 cases (38.6%). Mean duration of mechanical ventilation was 4.18 days (+/-2.17 SD). Mean ICU stay was 8.01 days (+/-3.63 SD). Mean hospital stay was 17.8 days (+/-10.47 SD). Eleven (12.5%) patients died in the early post-operative period. There were 3 late deaths, 2 of which occurred in infra-cardiac TAPVC patients, while the third was of mixed TAPVC type.


Conclusions: Early mortality was found to be 12.5%, while late mortality was 3.9%. All the patients included in our study have been operated by a single surgeon, thus eliminating bias. Our study emphasizes the fact that the overall outcome of TAPVC repair has improved compared to previous similar studies, mostly as a result of advancement of management strategies, both medical and surgical.

Abstract 36 | PDF Downloads 19

References

1. Wilson AD: Total anomalous pulmonary venous connection. eMedicine. Available at: http://www.emedicine.com/ped/topic254.
2. Patricia Stein RN: Total Anomalous Pulmonary Venous Connection. AORN Journal - Wiley Online Library [Internet]. 2007, 10.1016/S0001-2092(07)60123-9
3. Kanter KR: Surgical Repair of Total Anomalous Pulmonary Venous Connection. Seminars in Thoracic & Cardiovascular Surgery: Pediatric Cardiac Surgery Annual. 20061, 9:40-4. 10.1053/j.pcsu.2006.02.015
4. Burroughs JT, Edwards JE: Total anomalous pulmonary venous connection. American Heart Journal. 1960, 59:913-31. 10.1016/0002-8703(60)90414-2
5. Kirshbom PM, Myung RJ, Gaynor JW, Ittenbach RF, Paridon SM, DeCampli WM.: Preoperative pulmonary venous obstruction affects long-term outcome for survivors of total anomalous pulmonary venous connection repair. The. Annals of Thoracic Surgery. 2002, 1:1616-20. 10.1016/s0003-4975(02)03935-8
6. Hancock Friesen CL, Zurakowski D, Thiagarajan RR, Forbess JM, del Nido PJ, Mayer JE.: Total Anomalous Pulmonary Venous Connection: An Analysis of Current Management Strategies in a Single Institution. The. Annals of Thoracic Surgery. 2005, 79:596-606. 10.1016/j.athoracsur.2004.07.005
7. Morales DLS, Braud BE, Booth JH, Graves DE, Heinle JS, McKenzie ED.: Heterotaxy Patients With Total Anomalous Pulmonary Venous Return: Improving Surgical Results. The. Annals of Thoracic Surgery. 2006, 82:1621-8. 10.1016/j.athoracsur.2006.05.053
8. Tanel RE, Kirshbom PM, Paridon SM, Hartman DM, Burnham NB, McBride MG.: Long-term noninvasive arrhythmia assessment after total anomalous pulmonary venous connection repair. American Heart Journal. 2007, 153:267-74. 10.1016/j.ahj.2006.11.003
9. Herlong JR, Jaggers JJ, Ungerleider RM: Congenital Heart Surgery Nomenclature and Database Project: pulmonary venous anomalies. Ann Thorac Surg. 2000, 69:56-69. 10.1016/S0003-4975(99)01237-0
10. Bhan A, Sharma R, Iyer KS, Venugopal P: Improved exposure of TAPVC repair by posterior approach [Letter]. Ann Thorac Surg. 1996, 62:1000.
11. Malm JR: Secundum atrial septal defects and associated anomalous pulmonary venous drainage. In: Cooper P, ed. The craft of surgery. Boston, Massachusetts: Little Brown. 1964, 546:62.
12. Bando K, Turrentine MW, Ensing GJ, Sun K, Sharp TG, Sekine Y.: Surgical management of total anomalous pulmonary venous connection. Thirty-year trends. Circulation. 19961, 94:12-16.
13. Michielon G, Gharagozloo F, Julsrud PR, Danielson GK, Puga FJ: Modified Fontan operation in the presence of anomalies of systemic and pulmonary venous connection. Circulation. 1993, 88:141-148.
14. Lemaire A, DiFilippo S, Parienti JJ, Metton O, Mitchell J, Hénaine R.: Total Anomalous Pulmonary Venous Connection: A 40 years’ Experience Analysis. Thorac Cardiovasc Surg. 2017, 65:9-17. 10.1055/s-0036-1588007
15. Choudhary SK, Bhan A, Sharma R, Mathur A, Airan B, Saxena A.: Repair of total anomalous pulmonary venous connection in infancy: experience from a developing country. The. Annals of Thoracic Surgery. 1999, 68:155-9. 10.1016/S0003-4975(99)00375-6
16. Xiang M, Wu C, Pan Z, Wang Q, Xi L: Mixed type of total anomalous pulmonary venous connection: diagnosis, surgical approach and outcomes. J Cardiothorac Surg. 20202, 15:293. 10.1186/s13019-020-01332-7
17. Harada T, Nakano T, Oda S, Kado H: Surgical results of total anomalous pulmonary venous connection repair in 256 patients. Interact Cardiovasc Thorac Surg. 20191, 28:421-6. 10.1093/icvts/ivy267
18. Kelle AM, Backer CL, Gossett JG, Kaushal S, Mavroudis C: Total anomalous pulmonary venous connection: results of surgical repair of 100 patients at a single institution. J Thorac Cardiovasc Surg. 2010, 139:1387-1394. 10.1016/j.jtcvs.2010.02.024
19. Yong MS, Yaftian N, Griffiths S, Brink J, Robertson T, D’Orsogna L.: Long-Term Outcomes of Total Anomalous Pulmonary Venous Drainage Repair in Neonates and Infants. Ann Thorac Surg. 2018, 105:1232-8. 10.1016/j.athoracsur.2017.10.048
20. Sugano M, Murata M, Ide Y, Ito H, Kanno K, Imai K.: Midterm results and risk factors of functional single ventricles with extracardiac total anomalous pulmonary venous connection. Gen Thorac Cardiovasc Surg. 2019, 67:941-8. 10.1007/s11748-019-01141-3
21. Sakamoto T, Nagashima M, Umezu K, Houki R: Ikarashi J, Katagiri J, et al. Long-term outcomes of total correction for isolated total anomalous pulmonary venous connection: lessons from 50-years’ experience†. Interactive CardioVascular and Thoracic Surgery. 2018, 1:20-6. 10.1093/icvts/ivy034
22. Elamry E, Alkady HM, Menaissy Y, Abdalla O: Predictors of In-Hospital Mortality in Isolated Total Anomalous Pulmonary Venous Connection. Heart Surg Forum. 2019, 22:191-6. 10.1532/hsf.2415
23. Adzamli IK, Gaikwad S, Garekaar S, Mali S, Naseer NB, Agarwal V: Experience with the superior approach (Tucker’s repair) for repair of supracardiac total anomalous pulmonary venous connection (TAPVC). Indian Journal of Thoracic and Cardiovascular Surgery. 2016, 1:12-6. 10.1007/s12055-015-0410-5
24. Domadia S, Kumar SR, Votava-Smith JK, Pruetz JD: Neonatal Outcomes in Total Anomalous Pulmonary Venous Return: The Role of Prenatal Diagnosis and Pulmonary Venous Obstruction. Pediatr Cardiol. 2018, 39:1346-54. 10.1007/s00246-018-1901-0
25. Bayya PR, Varghese S, Jayashankar JP, et al.: Total anomalous pulmonary venous connection repair: Single-center outcomes in a lower-middle income region. World Journal for Pediatric and Congenital Heart Surgery. 2022, 13:458-65. 10.1177/215013512211034
26. Shentu J, Shi G, Zhang Q, et al.: Surgical repair of neonatal total anomalous pulmonary venous connection: A single institutional experience with 241 cases. JTCVS Open. 2023, 1:739-54. 10.1016/j.xjon.2023.07.021
27. Talwar S, Arora Y, Gupta SK, Kothari SS, Ramakrishnan S, Saxena A, et al. Total anomalous pulmonary venous connection beyond the first decade of life. World J Pediatr Congenit Heart Surg 2019; 10: 185–91.
28. Tailor KB, Dharmani KH, Kadam SV, Kattana HB, Rao SG A single center, retrospective analysis of total anomalous pulmonary venous connection repair early outcome at a tertiary care center in India. Ann Card Anaesth 2021; 24: 333–8.