A STUDY OF ASSOCIATION BETWEEN TRIGLYCERIDE GLUCOSE INDEX AND THE RISK OF ACUTE KIDNEY INJURY IN CRITICALLY ILL PATIENTS WITH ACUTE PANCREATITIS
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Keywords
Triglyceride Glucose index, Acute pancreatitis, Acute kidney injury
Abstract
Background: Acute pancreatitis (AP) is often complicated by acute kidney injury (AKI), significantly increasing morbidity and mortality in critically ill patients. The triglyceride-glucose (TyG) index has recently emerged as a marker of insulin resistance and potential predictor of adverse outcomes. This study evaluates the association between the TyG index and the risk of AKI in critically ill patients with AP.
Methods: A retrospective observational study was conducted over 2 years on 40 patients diagnosed with acute pancreatitis and admitted to the intensive care unit (ICU). The TyG index was calculated, and its correlation with the incidence of AKI was analyzed. A threshold TyG index level of 8.78 was considered significant for AKI risk prediction.
Results: Of 40 patients, 21 (52.5%) developed AKI. The mean TyG index was significantly higher in AKI patients compared to non-AKI patients. Patients with a TyG index above 8.78 had a notably increased risk of AKI.
Conclusion: The TyG index is a potential early marker for predicting AKI in critically ill AP patients. Early identification can help risk stratification and optimize clinical management.
References
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Dr. Yeshavanth.G
Professor and HOD, Department of General Medicine, S S Institute of Medical Sciences and Research Centre Davangere, Karnataka.
Dr. Kavana. K. B
Junior Resident, Department of General Medicine, S S Institute of Medical Sciences and Research Centre, Davangere, Karnataka.