A CLINICAL COMPARATIVE STUDY OF ANALGESIC EFFECT OF INJECTION 0.125% BUPIVACAINE, INJECTION TRAMADOL, INJECTION DEXAMETHASONE, GIVEN EPIDURALLY IN CASES OF INFRA UMBILICAL SURGERIES
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Keywords
VAS score, post-operative pain, Epidural analgesia, infraumbilical surgeries.
Abstract
Introduction: Epidural anaesthesia for post-operative pain relief offers advantages for patients who has undergone infraumbilical surgeries. This study aims to compare three drugs- Dexamethasone, 0.125% Bupivacaine and tramadol for post-op epidural analgesia.
Methodology: The study was done on 90 patients. After getting informed written consent, patients were explained about Verbal numerical/Analog scale for assessment of pain. Patients were given Subarachnoid block and Epidural catheter was fixed under local anaesthesia under strict aseptic conditions. During post-operative period, patients were assigned randomly to three groups B, D and T for Inj. 0.125% Bupivacaine, Inj Dexamethasone, and Inj Tramadol respectively. Patients were monitored for effective post operative analgesia (VAS score), duration of post operative analgesia, hemodynamic changes and postoperative side effects like hypotension, respiratory depression, nausea, vomiting and urinary retention.
Result: Our study has showed that the onset of pain relief for Dexamethasone was 24.8(±6.48), Bupivacaine was 21.4(±6.63) and for Tramadol 29.16(±6.63). The duration of analgesia is observed to be higher for Dexamethasone which was 5.64(±1.34) hours, followed by Tramadol 5.44(±1.7) hours and Bupivacaine was 4.55(±1.22). So, our study has concluded that Dexamethasone has provided adequate analgesia via epidural administration for infra-umbilical surgeries than 0.125% Bupivacaine and Tramadol.
Conclusion: Dexamethasone can be preferred as a better alternative for epidural analgesic agent for post operative pain relief with stable haemodynamic.
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Dr. Sukriti Atram
Associate Professor, Department of Anaesthesiology and Critical care, Grant Government Medical College & J.J groups of Hospital, Mumbai
Dr. Tushar Kharat
Clinical assistant, Department of Anaesthesiology, P D Hinduja Hospital, Mumbai
Dr. Subashini KJ
Junior resident -3, Department of Anaesthesiology and Critical care, Grant Government Medical College& J.J groups of Hospital, Mumbai