SEROPREVALENCE OF TRANSFUSION TRANSMITTED INFECTIONS IN A HEALTHY BLOOD DONORS : A 4 YR STUDY DONE IN A TERTIARY CARE CENTRE
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Keywords
KEYWORDS- Blood donation, Transfusion transmitted infection (TTI) ,HIV infection, Hepatitis B virus(HBV).
Abstract
Blood transfusion is an effective treatment for saving millions of lives, even though transfusion transmissible infections are a major problem. Transfusion transmitted infections (TTI) can cause threat to blood safety as blood transfusion is an important mode of transmission of Transfusion transmitted infections to the recipient, hence to prevent transmission of these diseases, screening tests on blood bags is an important step for blood safety.
Aim –To study the prevalence of transfusion transmitted infections among blood donors in a tertiary care hospital in India
Materials and Methods-A retrospective study was carried out over a period of 4 years from January 2021 to December 2024 at the blood bank of a tertiary care hospital in India .Serum samples were screened for Hepatitis B virus, Hepatitis C virus, Human immunodeficiency virus (HIV), Syphilis and Malaria.
RESULTS-A Total of 19305 voluntary and replacement donors were screened. The overall seroprevalence of
HIV ,Hepatitis B virus , Hepatitis C Virus and Syphilis were 17,178,03,03 respectively.
CONCLUSION- Blood is still one of the main sources of transmission of infections such as HIV, HBV, HCV, SYPHILIS. The present study show higher prevalance of Hepatitis B virus ,HIV, HCV and Syphilis respectively in a decreasing order. Proper screening of blood donors ,use of highly sensitive techniques for the detection of TTI S and improved post donation counselling are highly recommended to ensure the safety of blood for recipients.
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Dr Sheetal Balaji Gajale
Assistant Professor, Dept 0f Pathology, Dr S C Gmc, Nanded .
Dr Prashant Raviprakash Shinde
Surgeon ,District Hospital ,Chat Sambhaji Nagar.Dr Supriya R Muneshwar
Assistant professor, Srt Govt Medical College, AmbejogaiDr Deepak Sadhu
Associates professor, Gmc Hingoli.