TO STUDY THE EFFECT OF INTRAVENOUS MAGNESIUM SULPHATE ON ACUTE POST-OPERATIVE PAIN IN PATIENTS UNDERGOING LOWER LIMB ORTHOPEDIC SURGERIES UNDER SUBARACHNOID BLOCK: A PROSPECTIVE RANDOMIZED CONTROLLED STUDY
Main Article Content
Keywords
Magnesium Sulphate, Acute Postoperative Pain, Orthopedic Surgeries, Spinal Anesthesia, Randomized Controlled Trial, Visual Analogue Scale.
Abstract
Background
Acute postoperative pain remains a significant challenge following lower limb orthopedic surgeries. Although intravenous magnesium sulfate has shown promise in reducing postoperative pain in various surgical contexts, its role in orthopedic procedures, particularly under spinal anesthesia, remains underexplored. Magnesium, through NMDA receptor antagonism and calcium channel blockade, is hypothesized to enhance analgesic outcomes.
Methods
A prospective, randomized controlled trial was conducted at Government Medical College Sangareddy, Telangana from December 2023 to December 2024. A total of 116 patients aged 20–60 years undergoing elective lower limb orthopedic surgeries under spinal anesthesia were enrolled and randomized into two groups: Group A (n=58) received 1g intravenous magnesium sulphate preoperatively; Group B (n=58) did not receive magnesium. Standard spinal anesthesia with 0.5% hyperbaric bupivacaine was administered. Postoperative pain scores were assessed using the VAS (Visual Analogue Scale) and the requirement for rescue analgesia (inj. fentanyl 1mcg/kg IV) was recorded for 24 hours.
Results
There were no statistically significant differences in demographic characteristics (age, gender, ASA grade) between the two groups. Patients who received intravenous magnesium sulphate (Group A) demonstrated significantly lower VAS pain scores at 24 hours compared to Group B. Furthermore, the need for rescue analgesia was reduced in Group A, indicating enhanced postoperative analgesia.
Conclusion
Preoperative intravenous administration of magnesium sulphate effectively reduces acute postoperative pain and the requirement for rescue analgesia in patients undergoing lower limb orthopedic surgeries under subarachnoid block. Magnesium sulphate can be considered a useful adjuvant for enhancing postoperative analgesia in this patient population.
References
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Dr. Patnana Pradeep Kumar
Assistant Professor, Department of Anaesthesiology, Government Medical College, Sangareddy, Telangana, India.
Dr. Dasari Preethi
Assistant Professor, Department of Anaesthesia & Critical Care, Osmania Medical College, Telangana, India.
Dr. Vuppu Bhavani
Assistant Professor, Department of Anaesthesia, Government Medical College, Sangareddy, Telangana, India.
Dr. Mamidi Ajay Kumar
Assistant professor, Department of Anaesthesiology, Government Medical College, Sangareddy, Telangana, India.