IN-HOSPITAL OUTCOMES OF PATIENTS WITH STEMI AND ITS CORRELATION WITH ADMISSION GLUCOSE LEVEL
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Keywords
ST-elevation myocardial infarction (STEMI), Admission Glucose Level, In-Hospital Outcomes, Hyperglycemia, Euglycemia
Abstract
Objective: To determine the in-hospital outcomes of patients with STEMI and its correlation with admission glucose level.
Methodology: The study comprised of 280 patients diagnosed with ST-elevation myocardial infarction (STEMI) enrolled during the period March 2023 till September 2023. Admission glucose levels and clinical and biochemical parameters were noted. Hyperglycemia was defined as blood glucose levels more than 140 mg/dl in our study. Hypertension was defined as systolic blood pressure more than 140 mmHg or diastolic blood pressure greater than 90 mmHg. Outcomes were noted in terms of mortality and compared with admission glycemia.
Results: 192 (68.57%) were male and 88 (31.43%) were female, with a mean age of 59.8 ±12 years. The hyperglycemic group included 106 patients (78 males, 73.58%; 28 female, 26.42%) and the euglycemic group 174 (114 male, 65.52%; 60 female, 34.48%; p = 0.03). 110 (39.28%) had hypertension. Of 98 (35.9%) diabetic patients hospitalized, 82 (77.36%) had hyperglycemia and 16 (22.64%) had euglycemia. Overall mortality was 7.71 (n = 16), 14 patients (17.07) among hyperglycemics and 02 (8.0%) among euglycemics.
Conclusion: In patients with STEMI, hyperglycemia significantly worsens in-hospital outcomes for patients. Higher death rates are seen in STEMI patients who had hyperglycemia at hospital admission.
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Muhammad Khalil
Post Graduate Resident, Department of Cardiology, PIMS, Islamabad.
Muhammad Shafique Arshad
Professor, Department of Cardiology, PIMS, Islamabad
Asma Zafar Khawaja
Medical Officer, Department of Cardiology, Federal General Polyclinic Hospital, Islamabad
Mahboob Ur Rehman
Associate Professor, Department of Cardiology, PIMS, Islamabad
Hidayatullah
Postgraduate Resident, Department of Cardiology, PIMS, Islamabad
Sumeet Kumar
House Officer, Department of Cardiology, PIMS, Islamabad
Shoaib Ahmed
Assistant Laboratory Technician, PIMS, Islamabad