Regenerative Endodontic Management Of An Immature Non Vital Permanent Molar Using Concentrated Growth Factor- A Case Report

Main Article Content

Janvi M Gandhi
Deepa Gurunathan

Keywords

Concentrated, growth, dental, office, Regenerative

Abstract

Background: Endodontic management of immature necrotic molar teeth has always been a challenge for clinicians. This case report highlights the use of concentrated growth factor, an autologous platelet concentrate as an effective bio-material in the regeneration of an immature tooth.
Case Description: A 14 year old girl reported to the dental office with pain in the lower left second molar. Revascularization procedure was carried out after obtaining parental consent. Following bleeding induction, CGF was prepared, placed, and condensed using pluggers in the root canal space, followed by the placement of mineral trioxide aggregate up to the level of CEJ. Entrance filling was then given with type IX GIC and the patient was followed up for 1 year. At the end of 1 year, the patient was devoid of pain and an increase in root canal thickness and length was seen.
Conclusion: Concentrated growth factor can be considered as an effective scaffold for regenerative treatment of immature necrotic teeth.
Clinical Significance: Concentrated growth factor provides good cell proliferation and osteoblastic differentiation as well as a rich growth factor content. Revascularization process is quicker in this case considering the young age of the patient.

Abstract 136 | pdf Downloads 89

References

1. Sofowora A, Ogunbodede E, Onayade A. The role and place of medicinal plants in the strategies for disease prevention. Afr J Tradit Complement Altern Med. 2013 Aug 12;10(5):210–29.
2. Pinnamaneni R. Nutritional And Medicinal Value Of Papaya (Carica Papaya Linn.) [Internet]. World Journal of Pharmacy and Pharmaceutical Sciences. 2017. p. 2559–78. Available from: http://dx.doi.org/10.20959/wjpps20178-9947
3. Zhang JM, An J. Cytokines, inflammation, and pain. Int Anesthesiol Clin. 2007 Spring;45(2):27–37.
4. Yasasve M, Manjusha M, Saravanan M. Polymorphism in pro-inflammatory cytokines and their genetic susceptibility towards oral precancerous lesions and oral cancer. Oral Oncol. 2022 Oct;133:106027.
5. Dr. Duke’s phytochemical and ethnobotanical databases [Internet]. Vol. 38, Choice Reviews Online. 2001. p. 38–3317. Available from: http://dx.doi.org/10.5860/choice.38-3317
6. Khayat B, Jouanny G. Microsurgical Endodontics. Quintessence Publishing (IL); 2019.
7. Ma J, Al-Ashaw AJ, Shen Y, Gao Y, Yang Y, Zhang C, et al. Efficacy of ProTaper Universal Rotary Retreatment system for gutta-percha removal from oval root canals: a micro-computed tomography study. J Endod. 2012 Nov;38(11):1516–20.
8. Indi S, Desai SR, Hambire A, Mustafa M, Almokhatieb AA, Abuelqomsan MAS, et al. Comparison of the Time Required by Six Different Retreatment Techniques for Retrieval of Gutta-Percha: An In Vitro Study [Internet]. European Journal of General Dentistry. 2022. Available from: http://dx.doi.org/10.1055/s-0042-1750089

Most read articles by the same author(s)