Prediction Of Respiratory Morbidities In Neonates Using Cord Blood Arterial Lactate And Base Excess

Aditi D Bakare; J.M Pawar; K.Mahendranath; Shreshta.B.R; Subhangi Misal

doi:10.47750/jptcp.2023.30.16.008

Aditi D Bakare

Junior Resident, Department of Paediatrics, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India.

J.M Pawar

Associate Professor, Department of Paediatrics, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India

K.Mahendranath

Senior resident, Department of Paediatrics, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India

Shreshta.B.R

Senior resident, Department of Paediatrics, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India

Subhangi Misal

Senior resident, Department of Paediatrics, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India

Keywords

Respiratory, Lactate, Prediction, blood

Abstract

Background: The umbilical blood gas analysis is a valid tool for the evaluation of neonatal acidemia. Knowledge of the fetal acid-base status and detection of acidemia at the time of delivery can serve as a sensitive and accurate component in the assessment of a neonate’s risk of morbidity and death.
Aims and Objectives: To assess the correlation between cord blood arterial lactate levels, base excess in neonates and the development of respiratory distress and the requirement of delivery room resuscitation. To assess whether umbilical cord arterial lactate is superior to pH for predicting short-term neonatal morbidity.
Material and Methods: Study design: hospital based observational study. Sample size:138. Study setting: Labor ward of Krishna Hospital, Karad. Study period: January 2021 to November 2022.Data analysis: SPSS software using relevant statistical method.
Results: 138 neonates were enrolled. Cord blood base excess levels were higher in neonates with respiratory distress and those requiring delivery room resuscitation. However, there was no significant association between cord blood lactate levels and outcomes assessed
Conclusion: Estimation of arterial base excess levels obtained from umbilical cord blood sampling during delivery may serve as a sensitive marker for predicting respiratory morbidities.

Abstract 96 | PDF Downloads 159

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Published

Jun 23, 2023

DOI https://doi.org/10.47750/jptcp.2023.30.16.008

How to Cite

Aditi D Bakare, J.M Pawar, K.Mahendranath, Shreshta.B.R, & Subhangi Misal. (2023). Prediction Of Respiratory Morbidities In Neonates Using Cord Blood Arterial Lactate And Base Excess. Journal of Population Therapeutics and Clinical Pharmacology, 30(16), 69–77. https://doi.org/10.47750/jptcp.2023.30.16.008