Levels of Serum IL-34 and Lipid profile in Type 2 Diabetes Mellitus Patients

Main Article Content

Zahraa Kadhim Abed
Zainab Hussein Mohammed

Keywords

IL-34, lipid profile, Inflammation, cardiovascular problems

Abstract

Diabetes mellitus type 2 (T2DM) is a growing global health issue that is inextricably related to the obesity epidemic. Because of hyperglycemia and individual components of the insulin resistance (metabolic) syndrome, people with T2DM are at a significant risk for both microvascular and macrovascular consequences. Environmental (fat, a poor diet, and physical inactivity, for example) and hereditary variables also contribute to the many pathophysiological disruptions that cause impaired glucose homeostasis in T2DMSeveral studies have been conducted to investigate the role of dyslipidaemia in the macrovascular complications of diabetes. The current investigation's purpose was to determine the prevalence, pattern, and the link between IL-34 and dyslipidemia in T2DM patients. This study involves sixty T2DM patients. 30 people who appear to be in good health served as the control. Both the patients and the controls are the same age and BMI. Lipid abnormalities were discovered in this research. T2DM is distinguished by a high frequency of dyslipidaemia. An increase in poor lipids causes a variety of problems, including cardiovascular disease (CVD). Inflammation causes the proinflammatory cytokine IL-34, which is more prevalent in T2DM patients. Abnormal lipids and IL-34 can be factors in cardiovascular disease.

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