Clinical characteristics and risk factors of patients with COVID-19 developing barotrauma

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Jamil Muqtadir Bhatti
Syed Ali Raza
Irshad Batool Abro
Tooba Khalid Khan
Quratulain Khan
Syed Ali Abbas
Hammad A. Siddique
FNU Sameeullah


COVID-19, Barotrauma, CPAP, BiPAP, NIV, pneumothorax


Background: At our hospital, people with COVID-19 (coronavirus disease 2019) had a high rate of pulmonary barotrauma. Therefore, the current study looked at barotrauma in COVID-19 patients getting invasive and non-invasive positive pressure ventilation to assess its prevalence, clinical results, and features.
Methodology: Our retrospective cohort study comprised of adult COVID-19 pneumonia patients who visited our tertiary care hospital between April 2020 and September 2021 and developed barotrauma.
Results: Sixty-eight patients were included in this study. Subcutaneous emphysema was the most frequent type of barotrauma, reported at 67.6%; pneumomediastinum, reported at 61.8%; pneumothorax, reported at 47.1%. The most frequent device associated with barotrauma was CPAP (51.5%). Among the 68 patients, 27.9% were discharged without supplemental oxygen, while 4.4% were discharged on oxygen. 76.5% of the patients expired because of COVID pneumonia and its complications.
In addition, 38.2% of the patients required invasive mechanical breathing, and 77.9% of the patients were admitted to the ICU.
Conclusion: Barotrauma in COVID-19 can pose a serious risk factor leading to mortality. Also, using CPAP was linked to a higher risk of barotrauma.

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